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Nrf2 Pathway: Toxin Detoxification, genes activated by Nrf2, natural pathways to activate Nrf2

Nrf2 Pathway: Increasing the Body’s Ability to Get Rid of Toxins

The Nrf2 (Nuclear factor erythroid 2–related factor) signaling pathway regulates the expression of antioxidants and phase II detoxification enzymes. It is a fundamental pathway important in how well your body functions. Your genetic variants in the NFE2L2 gene impact this NRF2 pathway.

Genes that Impact Ferritin Levels

Genes that Impact Ferritin Levels

Ferritin is the storage protein for iron in the body. Storing too little or too much iron can be an indicator of an underlying problem. Discover the genetic variants that impact ferritin and how to increase ferritin with supplements or foods.

Genetic Causes of Male Infertility

Genetic Causes of Male Infertility

Almost 10% of couples worldwide struggle with infertility. Learn more about your genetic susceptibility and dig deeper into the lifestyle factors that could affect your sperm.

Genetic variants that affect Heat Shock Proteins Reasons to upregulate and downregulate heat shock proteins

Heat Shock Proteins: Cellular Resilience

Heat shock proteins are activated by cells in response to a stressful condition, such as exposure to high heat. Learn more about the essentials of heat shock proteins, including how to activate them and the genetic variants that impact how well they work.

Selenium and Your Genes

Selenium and Your Genes

Selenium is a trace element found in certain foods. Learn how selenium is used in the body, why it is important, and how genetic variants can make someone more susceptible to problems with a selenium-deficient diet.

Depression, Genetics, and Mitochondrial Function

Depression, Genetics, and Mitochondrial Function

How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.

Melatonin: Key to Health and Longevity, melatonin synthesis pathway

Melatonin: Key to Health and Longevity

More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.