Serotonin: How your genes affect this neurotransmitter

check your 23andMe data for serotonin gene mutations

Serotonin… a word that brings to mind commercials showing happy brain neurons bouncing serotonin between them. There is a lot more to this molecule than most of us realize! What does serotonin do? About 90% of serotonin is made in the gut and regulates…

Hacking BDNF for weight loss

Brain-derived neurotrophic factor (BDNF) is a fascinating growth hormone that does a lot in our brains. So what does BDNF do? Quite a bit! It is involved in supporting neurons and neuronal growth in the brain; it also plays a role in long-term memory…

Is the nootropic drug modafinil likely to work for you?

modafinil genes

Modafinil is being used as a nootropic drug that increases alertness and gives a sense of well being — to some users. Like most drugs, individual results seem to vary.  One reason for the variation is a common genetic variation in the COMT gene….

Choline – An Essential Nutrient

I just finished listening to an interesting podcast featuring Dr. Zeisel, a researcher at the NC Nutrition Research Institute.  The interview discussed the body’s need for choline and the impact of some genetic variants on our ability to produce it in the body.  So…

Genetics of Grinding Your Teeth

It never fails to amaze me how many of our quirks and traits have a genetic basis.  A study that came out last week caught my eye. Bruxism, teeth grinding, is linked to a genetic variant. The study, Genetic polymorphisms in the serotoninergic system are…

COMT – A gene that affects your neurotransmitter levels

Having trouble with supplements containing methyl groups? Wondering why your neurotransmitters are out of balance? It could be due to your COMT genetic variants. What does the COMT gene do? The COMT gene codes for the enzyme catechol-O-methyltransferase which breaks down (metabolizes) the neurotransmitters dopamine, epinephrine,…

A little lithium orotate and B12 make the world a happier place… for some people.

It is funny sometimes, looking back on the journey you take to discover something new and personal to your health. For me, seeing first hand the power of supplementing with a little mineral (lithium orotate) was eye-opening as to the power of combining genetics…