Taurine: Healthspan, Mitochondrial Function, and Heart Health
Taking a deep dive into the science behind taurine – from antiaging supplement to heart and digestive health. Genetics plays a role in who may benefit most from supplemental taurine.
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Adiponectin levels, food choices, and genetics
Although production occurs in adipose tissue, those with more fat tissue usually have lower adiponectin levels. Lower adiponectin levels (and thus high inflammation) have links to chronic issues associated with obesity.
Selenium and Your Genes
Selenium is a trace element found in certain foods. Learn how selenium is used in the body, why it is important, and how genetic variants can make someone more susceptible to problems with a selenium-deficient diet.
DHEA and Your Weight
DHEA is a hormone that does a lot in the body – including influencing muscle mass and weight. This quick article examines just one aspect of DHEA: how it affects our weight. But the genetic variants included here also impact other impacts of DHEA in the body.
Alpha-1 Antitrypsin Deficiency: Genetic Raw Data, Carrier Effects, Interactions with TNF
A genetic mutation in the SERPINA1 gene causes alpha-1 antitrypsin deficiency. This increases a person’s susceptibility to COPD (chronic obstructive pulmonary disease) and, in some cases, cirrhosis of the liver. Knowing that you carry this mutation can be a great incentive to avoid smoking and to be kind to your liver.
Infertility and Genetics (for Women)
Your genes may be playing a role in your infertility — and knowing which genetic variants you carry may help you figure out solutions to try.
Opioid Receptors Genetic Variants and Addiction
Genetic variants in the ORPM1 gene impact both the amount of pain someone experiences and their response to opioid drugs. These variants are also important in susceptibility to opiate addiction. (Member’s article)
Asparagus Pee: Do You have the Gene Variant to Smell It?
Can you smell asparagus in your pee? It is a smell that is inescapable, overwhelming, and unique. Right? Well, some people actually have no idea how pungent it can be.
Genetics and Intelligence: IQ-Influencing Genes and Paths to Optimization
Hundreds of identified genes influence intelligence, from IQ scores to musical ability. Learn more about your intelligence strengths and ways to enhance your cognitive function.
Genetics and Food Allergies
Do you have a food allergy? Discover how environmental factors and genetic susceptibility can shape individual reactions.
Advanced Glycation End Products (AGEs): Genetics, Lifestyle, and Health Span
One cause of many of the diseases of aging is the buildup of advanced glycation end products (AGEs). Your genes interact with your diet – and cooking methods – in the build-up of AGEs. Learn whether this is something that is important for you to focus on. (Member’s article)
Elevated Fibrinogen: Risk factor for blood clots
Fibrinogen is a protein that is essential for creating blood clots when you get a wound. But higher levels of fibrinogen are a major risk factor for heart disease and DVT. Learn how your genes impact your fibrinogen level.
Back Pain: Genetics, Root Causes, and Solutions
For some people, back pain is a daily occurrence that drastically affects their quality of life. For others, it may be an intermittent nagging problem, often without rhyme or reason. Your genes play a role in whether disc degeneration gives you back pain.
CYP2A6: Breaking down nicotine and other medications
How many cigarettes a day a person smokes – and how hard it is for them to quit – is at least partly dependent on the CYP2A6 gene. This enzyme also metabolizes several important cancer drugs.
Coronary Artery Disease: Genetic Susceptibility to Heart Disease
Coronary artery disease (CAD) is heritable. Understanding your genes and a ‘heart healthy’ lifestyle can prevent heart attacks and death.
Berberine: Research, Benefits, Absorption, and Genetics
Berberine, a natural compound, is found in plants such as Oregon grape, barberry, and goldenseal. It has been a staple of Traditional Chinese Medicine for thousands of years. Take a look into the research and health benefits of this age-old compound.
Genetics of Double Eyelashes
Elizabeth Taylor stood out in many ways – in part because of her thick lashes. Turns out a genetic variant is the likely source of her double row of lashes. Learn more about this variant and its other associated risks.
Shilajit: Muscles, Bones, and Testosterone
Shilajit is a supplement that contains fulvic acid, metabolites, and minerals. It has been used for centuries in Ayurvedic medicine, and clinical trials show it has positive benefits for osteoporosis, testosterone, male infertility, and muscle recovery.
AMPD1 Deficiency: Post-exercise Muscle Soreness
Do you end up getting sore after pretty much every workout at the gym? It could be that a deficiency caused by the AMPD1 genetic variant is the cause.
How natural supplements can change circadian gene expression
Did you know that some supplements change the expression of your core circadian clock genes? Your core circadian rhythm genes are foundational to your health, and some supplements alter that rhythm.
Plasminogen Activator Inhibitor-1 (PAI-1): Regulator of Clotting
Plasminogen Activator Inhibitor (PAI-1) is an important enzyme in the regulation of the breakdown of blood clots and fibrosis. Genetic variants impact the amount of PAI-1.
GLP-1: Genetic Variants Related to GLP1 Weight Loss Drugs
GLP-1 receptor agonists are used for weight loss by increasing the body’s sensitivity to insulin and reducing hunger. However, genetic variants can alter the response in some people.
Prions: Genetic Mutations that Increase Prion Disease Risk
Prions are able to infect, causing the normal protein around them to also misfold. These misfolded proteins aggregate to cause neurogenerative disease. Susceptibility to prion diseases depends in part on your genes.
Frequently Asked Questions about 23 and Me Raw Data
Do you have questions about using your 23 and Me raw data? Check out people’s most common questions about using their 23 and Me gene information.
Motivation to exercise? It’s genetic.
A study in the journal Behavioral Brain Research paints a fascinating picture of why some people are more motivated to exercise. The study looked at the dopaminergic system to see how people’s genetic variants could alter the ‘reinforcing value’ of exercise.