TNF-alpha is a key inflammatory cytokine linked to autoimmune, cardiovascular, mood, and neurodegenerative diseases. Learn how TNF gene variants affect your risk and potential natural TNF inhibitors.
There are multiple causes of irritable bowel syndrome (IBS), and genetics can definitely play a role in IBS symptoms. Pinpointing your genetic cause may help you to figure out the right solution for you. (Member’s article)
Mannose-binding lectin, also known as mannose-binding protein, is involved in the body’s innate defense against infections. Find out how genetic variants in this system increase your susceptibility to specific pathogens.
Learn how IL-15 influences NK cells and CD8+ T cells in the immune response to pathogens and cancers. Find out how your genetic variants influence IL-15 levels.
Do your fingertips turn white and blue when cold? Discover the causes and symptoms of Raynaud’s syndrome and your genetic susceptibility.
Interleukin-13 (IL-13) is a signaling molecule important in the immune response. Excessive IL-13 can tip you toward a Th2-dominant immune response, and variants increase the risk of allergies and asthma.
A genetic variant in the FUT2 gene controls whether or not you secrete your blood type into your saliva and other bodily fluids, such as your intestinal mucosa. This can alter the gut microbiome – but protect against Norovirus infections.
Fibrinogen is a protein that is essential for creating blood clots when you get a wound. But higher levels of fibrinogen are a major risk factor for heart disease and DVT. Learn how your genes impact your fibrinogen level.
Explore how MEFV mutations drive autoinflammatory flares, the overlap of FMF with fibromyalgia, gout, lupus, and MCAS, and evidence-based options from colchicine to natural anti-inflammatory strategies.
Celiac disease is caused by a combination of environmental factors (eating gluten, other factors) and having the genetic variants that cause susceptibility to the disease. Without the genetic susceptibility, you won’t have celiac.
Genetic variants in tryptophan pathway enzymes alter quinolinic and kynurenic acids, NAD+ production, and serotonin synthesis. These genes influence mood, sleep, fatigue, immunity, and ong Covid brain fog risk.
Explore arsenic metabolism genes, including AS3MT, GSTO1, and MTHFR, plus practical ways to reduce arsenic exposure from water and food.
Genetics plays a role in the likelihood of having chronic sinus problems. This article looks at the genetic reasons driving some people to have chronic sinus infections.
The HLA-B27 serotype is linked to an increased risk of several autoimmune diseases, including ankylosing spondylitis, psoriatic arthritis, and IBD.
Emulsifiers, found in many processed and packaged foods, can trigger an inflammatory response in the intestines based on whether you carry specific genetic variants.
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
Partial IgA deficiency, which affects up to 1% of the population, can have a genetic component and overlaps with some autoimmune diseases.
Discover the pros and cons of fluoride for dental health and overall wellness, its sources, toxicity levels, and how genetics influence fluoride sensitivity.
Nickel allergy: Explore how genes, everyday exposures, and diet contribute to nickel sensitivity, including rashes, GI symptoms, and brain fog.
Discover the role of genetics, stress, and neurotransmitters in alcohol use disorder. Alcohol dependence is complex; understand your genes and the research on treatment options.
MS susceptibility is linked to both genetic causes and environmental factors. Learn how those two combine – and possible solutions.
Are you dealing with dry eyes and dry mouth? Sjögren’s syndrome is an autoimmune disorder that affects moisture-producing glands. Discover the underlying causes of Sjögren’s syndrome and the genetic variants that increase susceptibility.
Your genes control whether you are likely to produce lactase as an adult. Check your 23andMe or other genetic data to see if you are likely to enjoy a big glass of milk.
GABA (gamma-Aminobutyric acid) is a neurotransmitter that acts to block or inhibit a neuron from firing. It is an essential way that the brain regulates impulses, and low GABA levels are linked with several conditions, including anxiety and PTSD.
What are the physiological effects of mercury and how does the body eliminates it? Discover how genetic variants play a role in how quickly you excrete mercury.