Personalized Genetic Insights from Your DNA Data
Connect your 23andMe, AncestryDNA, Sequencing.com, TellMeGen, or other raw DNA data to get personalized health, nutrition, and longevity insights — with reports that run locally in your browser for 100% private analysis.
Tired of generic advice that doesn’t work for your health, your wellness?
Genetic Lifehacks is the top site for genetic insights, with a privacy focus that is unmatched.
- Step 1: Connect your raw DNA file on the Dashboard (e.g., 23andMe or AncestryDNA raw data format)
- Step 2: Instantly see your genetic reports – along with detailed explanations of ‘why’
- Step 3: View the solutions; choose what works for YOU.
All genotype reports cite current peer‑reviewed studies, so you can verify and dig deeper.
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The only major DNA analysis platform that keeps your genetic data 100% private.
- Reports run locally
- No uploading your data, no storage of your private genetic information
- No tracking with ads, Meta pixels, or Google analytics
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Latest Genotype Reports:
- Blood-Brain Barrier Genes: SNPs, Leaky BBB Risks & Solutions
Genetic variants can increase susceptibility to blood-brain barrier (BBB) dysfunction. This can increase the risk of Alzheimer’s, ADHD, and mood disorders. - TRPM3: The Ion Channel Behind Pain, Migraines, and ME/CFS
TRPM3 is a calcium ion channel involved in heat sensing, pain transmission, migraines, and immune function. Your TRPM3 gene variants may affect susceptibility to ME/CFS, long Covid, and chronic pain. - Taurine: Healthspan, Mitochondrial Function, and Heart Health
Taking a deep dive into the science behind taurine – from antiaging supplement to heart and digestive health. Genetics plays a role in who may benefit most from supplemental taurine. - Lipoprotein(a): Genetics and Lp(a) Levels
High Lp(a) levels are a big risk factor for sudden heart attacks. Your Lp(a) levels are mainly controlled by your genetic variants. Check to see if you carry genetic variants that increase or decrease Lp(a). - TRPV1 Gene: Receptor for Spicy Foods, Sensing Cold, and CBD Oil
Learn how the TRPV1 gene shapes your reaction to spicy foods, pain, temperature, neuroinflammation and CBD oil, plus see how your genetic variants may affect tolerance and health. - Candida Biology, Pathogenesis, and Genetic Susceptibility
Learn why genetic variants in IL‑17, TLRs, dectin‑1, MBL, FUT2, and STAT1 can make some people much more susceptible to chronic or severe Candida infections. - AHCC: Mushroom Compound That Modulates NK and T Cells
AHCC, a mushroom extract, boosts NK cells and T cells. Learn what the studies show for HPV, immune health, and chemotherapy support — plus drug interactions. - Genetics of Mannose-Binding Lectin (MBL) Deficiency
Mannose-binding lectin, also known as mannose-binding protein, is involved in the body’s innate defense against infections. Find out how genetic variants in this system increase your susceptibility to specific pathogens. - IL-2 Genetics and Immune Balance
IL-2 dysregulation affects long COVID, autoimmune diseases, and cancer therapy response. Learn about your IL-2 genetic variants and natural ways to support IL-2.
Recently updated:
Staying up to date with new research is important! Check out these genotype reports that have been updated:
Psychopaths: Born not made?
This article explains how MAOA, OXTR, LINC00951, HTR2B, and SNAP25 variants, childhood abuse, toxins, and epigenetic shifts combine to raise psychopathy risk — without predestining anyone to become a violent offender.
Circadian Rhythm Disruption as a Root Cause of Depression
Circadian clock gene variants in CLOCK, BMAL1, PER, CRY, NPAS2, and OPN4 interact with light exposure to disrupt hormones, sleep, and mood, increasing risk for depression, anxiety, and seasonal affective disorder.
VMAT2 gene: The God Gene and Neurotransmitters
VMAT2, the so‑called “God gene,” packages dopamine, serotonin, and other monoamines into vesicles, protecting neurons from oxidative stress and influencing risks for Parkinson’s, PTSD, alcohol dependence, and diabetes.
GABA: Genetics, Anxiety, and Immune Response
GABA (gamma-Aminobutyric acid) is a neurotransmitter that acts to block or inhibit a neuron from firing. It is an essential way that the brain regulates impulses, and low GABA levels are linked with several conditions, including anxiety and PTSD.
Tryptophan Pathways: Kynurenine, Serotonin, and Melatonin
Genetic variants in tryptophan pathway enzymes alter quinolinic and kynurenic acids, NAD+ production, and serotonin synthesis. These genes influence mood, sleep, fatigue, immunity, and ong Covid brain fog risk.
Dopamine Synthesis SNPs: Genes, lifestyle, diet, and dopamine optimization
Genetic variants in dopamine synthesis and breakdown genes interact with circadian rhythm, gut microbes, nutrients, and toxins, shaping risks for procrastination, psychosis, hypertension, Parkinson’s, and addiction.
Glutamate: Synthesis, transport, and supplement interactions
Glutamate, the main excitatory neurotransmitter, is tightly regulated through synthesis, transporters, and GABA balance, with genetic variants influencing risk for migraines, OCD, seizures, and schizophrenia.
Neuropilins: Neurodevelopmental Disorders, Gut Barrier, & Covid Brain
Explore how neuropilin variants shape neurodevelopment, vascular permeability, gut barrier function, viral entry (SARS‑CoV‑2, EBV, CMV), and risks for autoimmunity and cancer.
Opioid Receptors Genetic Variants and Addiction
Genetic variants in the ORPM1 gene impact both the amount of pain someone experiences and their response to opioid drugs. These variants are also important in susceptibility to opiate addiction.
Explore by Symptoms, Supplements, Diet, or Pathway:
Symptoms
allergies anemia anxiety arthritis blood pressure brain fog depression dysautonomia eyes fatigue gallbladder hair loss heavy menstrual bleeding high blood pressure intestinal issues itching migraine migraines neuropathy pain peripheral nerves POTS sinus skin small fiber neuropathy stress teeth tinnitus tremor
Supplements
Akkermansia muciniphila alpha-ketogluterate alpha-lipoic acid andrographis apigenin ashwagandha astaxanthin astragalus bacopa berberine biotin calcium calcium d-glucurate carnitine cat's claw CBD cinnamon copper CoQ10 cordyceps creatine curcumin d-mannose dihydromyricetin EGCG fisetin fish oil frankincense ginkgo biloba ginseng glycine glycyrrhizin hesperidin inositol iodine l-arginine l-theanine lion's mane lithium orotate lutein luteolin magnesium manganese melatonin methylene blue methylfolate NAC naringenin nattokinase niacin nicotinamide riboside nigella sativa NMN noopept PEA peppermint probiotics quercetin reishi resveratrol rhodiola riboflavin rosemary rosmarinic acid rutin selenium St. Johns wort sulforaphane taurine thiamine TUDCA vitamin A vitamin B12 vitamin B6 vitamin C vitamin D vitamin E vitamin K zinc
Pathways & Processes
acetylcholine AGEs anandamide arachidonic acid autophagy bile acids bone brown fat cannabinoids catecholamines cholesterol circadian rhythm clots cognitive cold collagen complement system connective tissue dopamine endothelium GABA ghrelin glutathione GSTs gut microbiome HbA1c heat shock proteins histamine hypoxia inborn error of metabolism inflammation intelligence klotho lactose lungs macrophages mannose binding lectin mast cells methylation microbiome mitochondria mTOR muscle neurons non-secretor oxidative stress plant sterols platelets pro-resolving mediators senescence serotonin sirtuins T cells taste receptor triglycerides tryptophan tyramine uric acid vagus nerve vascular
Diseases, Conditions
adenovirus ADHD alpha-1 antitrypsin Alzheimer's asthma autism bipolar cancer celiac cystic fibrosis diabetes dry eyes Ehlers-Danlos epilepsy Epstein-Barr virus fibroids fibromyalgia flu gout heart hemochromatosis IBD infertility lupus lyme macular degeneration ME/CFS miscarriage multiple sclerosis NAFLD nickel obesity osteoporosis osteoporsis Parkinson's PCOS periodontal periodontitis Propionibacterium acnes psoriasis rheumatoid arthritis rosacea seasonal affective disorder Sjogren vaccination vaccines virus
Lifestyle & Diet
acupuncture alcohol anthocyanins aspartame athletics caffeine carbs choline coffee corn syrup cruciferous vegetables fasting fiber fodmaps fructose gluten healthspan iron keto light at night liver longevity organic PFOS polyphenols saturated fat sauna sleep
Genes, Proteins
ACE ADAMS adora2a APOE BDNF BH4 CCR5 COMT Covid GLP-1 GSTM1 GSTP1 hemoglobin HLA HMGB1 homocysteine HPA IGF1 IL-13 IL-17 IL-18 IL-1A IL-1B IL-6 interferon-gamma lp(a) MAO NF-kB nitric oxide NLRP3 telomeres TLR4 TNF-alpha TRPV1 UGTs X chromosome
Hormones
Medications
anesthesia antibiotics aspirin CYP450 drugs metformin nicotine NSAIDs psychodelics rapamycin statins
Toxins
My Story…
Hi! I’m Debbie Moon, founder of Genetic Lifehacks.
When I first had my genetic data sequenced, I was both amazed and frustrated: amazed by all of the genetic research available in academic journals, but frustrated by the disconnected topics and lack of accessibility.
I started Genetic Lifehacks to bridge the gap — to help everyone understand how their genes influence their health, diet, and longevity with practical and useful information based on current research studies.
With my undergraduate degree in engineering as a foundation and a Master’s degree in Biological Sciences from Clemson University (2019), I’ve built Genetic Lifehacks into a platform that has helped over 5 million readers and 19,000+ members to optimize their health through understanding their genetics.
~ Debbie
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