Learn from Your DNA Data
Connect to your raw data from 23andMe, AncestryDNA, MyHeritage, Sequencing.com, TellMeGen, or other raw DNA data to get personalized health, nutrition, and longevity insights.
Tired of advice that doesn’t work for your health, your wellness? Use your genetic data to find out what is more likely to work for you. Genetic Lifehacks is the top site for genetic insights. For more than 10 years, Genetic Lifehacks has provided high-quality and usable information on genetics and health – all based around your genetic raw data.
It’s easy to get started:
- Step 1: Sign up as a member and connect your raw DNA file on the Dashboard
- Step 2: Instantly see your genetic reports, along with detailed explanations of ‘why’
- Step 3: View the solutions – the lifehacks – and choose what works for YOU.
More than just a genetic report site:
Genetic Lifehacks explains the background science in-depth, giving you the ability to truly understand what’s going on in your body. Expert-chosen, curated research is explained (by humans), along with the background context so that you can see how to apply the information to your situation.
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The only major DNA analysis platform that keeps your genetic data 100% private.
- Reports and member features run locally on your computer
- No storage of your private genetic information
- No tracking you with ads, Meta pixels, or Google Analytics
- No financial bias, no selling you supplements
Explore by topic hub:
Latest Genotype Reports:
- Hypophosphatasia (HPP) and the ALPL Gene
Hypophosphatasia (HPP) is a genetic disorder caused by ALPL mutations that lower alkaline phosphatase (ALP), leading to bone, dental, and vitamin B6-related issues. Learn how low ALP is diagnosed and supported in adults. - NQO1 Gene: Metabolism of Quinones, Benzene, and More
The NQO1 gene codes for an important enzyme in phase II detoxification. This enzyme is responsible for metabolizing the cancer-causing benzene (e.g. from air pollution) and cigarette toxins. Learn more and check your genes. (Member’s article) - Norepinephrine: Focus, stress, genetics, and brain function
Discover how norepinephrine and your genes affect ADHD, ME/CFS, long COVID, POTS, and mood, plus evidence‑based ways to support healthy norepinephrine balance. - Drug-Induced Depletions: Medications and Missing Micronutrients
Common medications can deplete micronutrients, especially when combined with a genetic susceptibility to lower levels of certain vitamins or minerals. If you’re on any prescription drugs, check your genes and consider testing your micronutrient levels. - Dopamine and Digital Addictions: Internet Use, Gaming, and Smartphones
Genetics plays a role in susceptibility to addictive behavior, including internet and smartphone addiction. This article examines the latest fad of dopamine fasting along with genetic variants tied to internet use problems, smartphone usage disorder, and gaming disorders. - Blood-Brain Barrier Genes: SNPs, Leaky BBB Risks & Solutions
Genetic variants can increase susceptibility to blood-brain barrier (BBB) dysfunction. This can increase the risk of Alzheimer’s, ADHD, and mood disorders. - TRPM3: The Ion Channel Behind Pain, Migraines, and ME/CFS
TRPM3 is a calcium ion channel involved in heat sensing, pain transmission, migraines, and immune function. Your TRPM3 gene variants may affect susceptibility to ME/CFS, long Covid, and chronic pain. - Taurine: Healthspan, Mitochondrial Function, and Heart Health
Taking a deep dive into the science behind taurine – from antiaging supplement to heart and digestive health. Genetics plays a role in who may benefit most from supplemental taurine. - Lipoprotein(a): Genetics and Lp(a) Levels
High Lp(a) levels are a big risk factor for sudden heart attacks. Your Lp(a) levels are mainly controlled by your genetic variants. Check to see if you carry genetic variants that increase or decrease Lp(a).
Recently updated:
Staying up to date with new research is important! Check out these genotype reports that have been updated:
Small Fiber Neuropathy: Genetics, Causes, and Possible Solutions
Small Fiber Neuropathy (SFN) results in burning pain, numbness, odd sensations, or autonomic nervous system issues. Learn more about the possible causes and potential solutions to this debilitating disorder.
Plasmalogens: Healthy Brain Aging and More
Plasmalogen levels in the brain are key to brain health. Low plasmalogen is linked to Alzheimer’s and ME/CFS. Healthy ways to boost your levels.
Genetic Mutations that Protect Against Alzheimer’s Disease
Just like there are genetic variants that increase the risk of Alzheimer’s, there are also variants that protect against this disease. Check your genetic data to get a better picture of your risk factors. (Member’s article)
Reelin – Long Covid, Depression, and Alzheimer’s
Reelin is a key glycoprotein involved in brain development, cognition, and neurodegenerative diseases like Alzheimer’s, schizophrenia, autism, and cardiovascular health.
Convert Your BAM/CRAM or VCF Whole Genome File to a Raw Data Format
Directions on converting a whole genome file into a .txt format that can be used on Genetic Lifehacks.
ACTN3 Gene: Deficiency and Muscle Type
The ACTN3 gene codes for actinin alpha-3, a protein found in fast-twitch muscles. Some people don’t produce this protein, which changes the composition of their muscles. Elite athletes may be limited by this genetic change.
Lactose Intolerance: How to Check Your Genetic Data
Your genes control whether you are likely to produce lactase as an adult. Check your 23andMe or other genetic data to see if you are likely to enjoy a big glass of milk.
Back Pain: Genetics, Root Causes, and Solutions
For some people, back pain is a daily occurrence that drastically affects their quality of life. For others, it may be an intermittent nagging problem, often without rhyme or reason. Your genes play a role in whether disc degeneration gives you back pain.
Explore by Symptoms, Supplements, Diet, or Pathway:
Symptoms
allergies anemia anxiety arthritis blood pressure brain fog depression dysautonomia eyes fatigue gallbladder hair loss heavy menstrual bleeding high blood pressure intestinal issues itching migraine migraines neuropathy pain peripheral nerves POTS sinus skin small fiber neuropathy stress teeth tinnitus tremor
Supplements
Akkermansia muciniphila alpha-ketogluterate alpha-lipoic acid andrographis apigenin ashwagandha astaxanthin astragalus bacopa berberine biotin calcium calcium d-glucurate carnitine cat's claw CBD cinnamon copper CoQ10 cordyceps creatine curcumin d-mannose dihydromyricetin EGCG fisetin fish oil frankincense ginkgo biloba ginseng glycine glycyrrhizin hesperidin inositol iodine l-arginine l-theanine lion's mane lithium orotate lutein luteolin magnesium manganese melatonin methylene blue methylfolate NAC naringenin nattokinase niacin nicotinamide riboside nigella sativa NMN noopept PEA peppermint probiotics quercetin reishi resveratrol rhodiola riboflavin rosemary rosmarinic acid rutin selenium St. Johns wort sulforaphane taurine thiamine TUDCA vitamin A vitamin B12 vitamin B6 vitamin C vitamin D vitamin E vitamin K zinc
Pathways & Processes
acetylcholine AGEs anandamide arachidonic acid autophagy bile acids bone brown fat cannabinoids catecholamines cholesterol circadian rhythm clots cognitive cold collagen complement system connective tissue dopamine endothelium GABA ghrelin glutathione GSTs gut microbiome HbA1c heat shock proteins histamine hypoxia inborn error of metabolism inflammation intelligence klotho lactose lungs macrophages mannose binding lectin mast cells methylation microbiome mitochondria mTOR muscle neurons non-secretor oxidative stress plant sterols platelets pro-resolving mediators senescence serotonin sirtuins T cells taste receptor triglycerides tryptophan tyramine uric acid vagus nerve vascular
Diseases, Conditions
adenovirus ADHD alpha-1 antitrypsin Alzheimer's asthma autism bipolar cancer celiac cystic fibrosis diabetes dry eyes Ehlers-Danlos epilepsy Epstein-Barr virus fibroids fibromyalgia flu gout heart hemochromatosis IBD infertility lupus lyme macular degeneration ME/CFS miscarriage multiple sclerosis NAFLD nickel obesity osteoporosis osteoporsis Parkinson's PCOS periodontal periodontitis Propionibacterium acnes psoriasis rheumatoid arthritis rosacea seasonal affective disorder Sjogren vaccination vaccines virus
Lifestyle & Diet
acupuncture alcohol anthocyanins aspartame athletics caffeine carbs choline coffee corn syrup cruciferous vegetables fasting fiber fodmaps fructose gluten healthspan iron keto light at night liver longevity organic PFOS polyphenols saturated fat sauna sleep
Genes, Proteins
ACE ADAMS adora2a APOE BDNF BH4 CCR5 COMT Covid GLP-1 GSTM1 GSTP1 hemoglobin HLA HMGB1 homocysteine HPA IGF1 IL-13 IL-17 IL-18 IL-1A IL-1B IL-6 interferon-gamma lp(a) MAO NF-kB nitric oxide NLRP3 telomeres TLR4 TNF-alpha TRPV1 UGTs X chromosome
Hormones
Medications
anesthesia antibiotics aspirin CYP450 drugs metformin nicotine NSAIDs psychodelics rapamycin statins
Toxins
My Story…
Hi! I’m Debbie Moon, founder of Genetic Lifehacks.
When I first had my genetic data sequenced, I was both amazed and frustrated: amazed by all of the genetic research available in academic journals, but frustrated by the disconnected topics and lack of accessibility.
I started Genetic Lifehacks to bridge the gap — to help everyone understand how their genes influence their health, diet, and longevity with practical and useful information based on current research studies.
With my undergraduate degree in engineering as a foundation and a Master’s degree in Biological Sciences from Clemson University (2019), I’ve built Genetic Lifehacks into a platform that has helped over 5 million readers and 19,000+ members to optimize their health through understanding their genetics.
~ Debbie
Learn more About Genetic Lifehacks