Personalized Genetic Insights from Your DNA Data
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Genetic Lifehacks gives YOU the tools so that you can use your genetic raw data:
- Use your genetic raw data from 23andMe, AncestryDNA, MyHeritage, and more.
- See your genotypes in detailed articles and in summary reports.
- View the solutions; choose what works for YOU.
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‼️ New! Check out the personalized Methylation Cycle Report just for members.
Latest Articles + Genotype Reports:
- MMUT Gene Variants and Methylmalonic Acid: Genetics, B12 Status, and Mitochondrial Function
Discover how MMUT gene variants affect your B12 status. High methylmalonic acid (MMA) explains symptoms like fatigue and brain fog—and why adenosylcobalamin may help. - Thiamine: Genomics, Cellular Energy, and Cognitive Function
Also known as vitamin B1, thiamine is essential for energy production and brain function. Learn how your genes influence your need for thiamine. - Vitamin B5 (Pantothenic Acid): Genetics, Deficiency, and Neurodegenerative Disease
Pantothenic acid (vitamin B5) is essential for coenzyme A synthesis and brain energy. Learn about B5 deficiency, PANK2 mutations, and links to Alzheimer’s. - Borderline Personality Disorder: How Genes, Trauma, and Inflammation Interact
Genetics, epigenetics, and childhood trauma all contribute to BPD. Understand the neurotransmitter disruptions, inflammatory markers, and circadian rhythm issues—with solutions that work. - Artificial Sweeteners: Sucralose, Aspartame, and Genetic Interactions
Health Effects from Artificial Sweeteners; Clinical trials on Sucralose, Aspartame, and Genetic Interactions - Interleukin-15 (IL-15): Immune response, cancer, long Covid, and genetics
Learn how IL-15 influences NK cells and CD8+ T cells in the immune response to pathogens and cancers. Find out how your genetic variants influence IL-15 levels. - Gut Mucosal Barrier & Mucin Genes: Diet and DNA Shape Your Gut Defense
Your gut mucosa protects you from microbes in the gut, your own digestive enzymes, and toxins from the environment. Learn what you can do to keep your gut mucosal barrier healthy. - BChE gene: Nightshade sensitivity, Anesthesia risk
Genetic variants of the BChE gene decrease its enzyme’s activity. This can lead to various and seemingly unconnected consequences…such as an increased risk for Parkinson’s or food sensitivity to potatoes. - Nicotinamide Riboside and NMN: Boosting NAD+ in Aging with Supplements
Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.
Recently updated genetic reports + articles:
Staying up to date is important! Check out these articles that have been updated with new research:
Leptin Receptors: Genetics and Hunger
Do you wonder why other people don’t seem to struggle with wanting to eat more? Leptin is a hormone that signals to the brain when you are full and should stop eating. Genetic variants in the LEPR gene are linked to obesity and desire to eat more.
BHMT: Genetic Variants that Impact Methylation
BHMT is involved in homocysteine methylation and impacts the methylation cycle.
MTHFR, Depression, Anxiety, Symptoms and Treatment
We are all genetically unique, and a common genetic variant in the MTHFR gene causes some people to be more susceptible to having low folate levels. This article explains the research linking MTHFR variants, folate, and depression — and gives you information on how diet or supplements may help.
Genetic Reasons Why Low FODMAPs Isn’t Working For You (SI Gene)
The low FODMAPs diet is often recommended as a starting point for anyone with IBS symptoms but genetics can limit its effectiveness.
UCP1: Brown Fat and Increased Fat Burning
Some people have more active ‘internal heat’ and they actually are burning off more energy all the time. The UCP1 gene is important for mitochondrial energy use and heat production from brown fat. Genetic variants in UCP1 can cause weight gain and obesity.
CYP1A2 Gene: Fast or Slow Caffeine Metabolizer and More
The CYP1A2 gene breaks down caffeine, melatonin, several major prescription drugs, and interacts with smoking. Learn how your genes influence caffeine metabolism and more.
CYP2C8: Prescription Medications and Arachidonic Acid
The CYP2C8 gene is important in the metabolism of several chemotherapy drugs as well as playing a role in the metabolism of NSAIDs. Genetic variants that alter how this enzyme works can impact your reaction to a medication.
Explore by Symptoms, Supplements, Diet, or Pathway:
Symptoms
allergies anemia anxiety arthritis blood pressure brain fog depression dysautonomia eyes fatigue gallbladder hair loss heavy menstrual bleeding high blood pressure intestinal issues itching migraine migraines neuropathy pain peripheral nerves POTS sinus skin small fiber neuropathy stress teeth tinnitus tremor
Supplements
Akkermansia muciniphila alpha-ketogluterate alpha-lipoic acid andrographis apigenin ashwagandha astaxanthin astragalus bacopa berberine biotin calcium calcium d-glucurate carnitine cat's claw CBD cinnamon copper CoQ10 cordyceps creatine curcumin d-mannose dihydromyricetin EGCG fisetin fish oil frankincense ginkgo biloba ginseng glycine glycyrrhizin hesperidin inositol iodine l-arginine l-theanine lion's mane lithium orotate lutein luteolin magnesium manganese melatonin methylene blue methylfolate NAC naringenin nattokinase niacin nicotinamide riboside nigella sativa NMN noopept PEA peppermint probiotics quercetin reishi resveratrol rhodiola riboflavin rosemary rosmarinic acid rutin selenium St. Johns wort sulforaphane taurine thiamine TUDCA vitamin A vitamin B12 vitamin B6 vitamin C vitamin D vitamin E vitamin K zinc
Pathways & Processes
acetylcholine AGEs anandamide arachidonic acid autophagy bile acids bone brown fat cannabinoids catecholamines cholesterol circadian rhythm clots cognitive cold collagen complement system connective tissue dopamine endothelium GABA ghrelin glutathione GSTs gut microbiome HbA1c heat shock proteins histamine hypoxia inborn error of metabolism inflammation intelligence klotho lactose lungs macrophages mannose binding lectin mast cells methylation microbiome mitochondria mTOR muscle neurons non-secretor oxidative stress plant sterols platelets pro-resolving mediators senescence serotonin sirtuins T cells taste receptor triglycerides tryptophan tyramine uric acid vagus nerve vascular
Diseases, Conditions
adenovirus ADHD alpha-1 antitrypsin Alzheimer's asthma autism bipolar cancer celiac cystic fibrosis diabetes dry eyes Ehlers-Danlos epilepsy Epstein-Barr virus fibroids fibromyalgia flu gout heart hemochromatosis IBD infertility lupus lyme macular degeneration ME/CFS miscarriage multiple sclerosis NAFLD nickel obesity osteoporosis osteoporsis Parkinson's PCOS periodontal periodontitis Propionibacterium acnes psoriasis rheumatoid arthritis rosacea seasonal affective disorder Sjogren vaccination vaccines virus
Lifestyle & Diet
acupuncture alcohol anthocyanins aspartame athletics caffeine carbs choline coffee corn syrup cruciferous vegetables fasting fiber fodmaps fructose gluten healthspan iron keto light at night liver longevity organic PFOS polyphenols saturated fat sauna sleep
Genes, Proteins
ACE ADAMS adora2a APOE BDNF BH4 CCR5 COMT Covid GLP-1 GSTM1 GSTP1 hemoglobin HLA HMGB1 homocysteine HPA IGF1 IL-13 IL-17 IL-18 IL-1A IL-1B IL-6 interferon-gamma lp(a) MAO NF-kB nitric oxide NLRP3 telomeres TLR4 TNF-alpha TRPV1 UGTs X chromosome
Hormones
Medications
anesthesia antibiotics aspirin CYP450 drugs metformin nicotine NSAIDs psychodelics rapamycin statins
Toxins
My Story…
Hi! I’m Debbie Moon, founder of Genetic Lifehacks.
When I first had my genetic data sequenced, I was both amazed and frustrated: amazed by all of the genetic research available in academic journals, but frustrated by the disconnected topics and lack of accessibility.
I started Genetic Lifehacks to bridge the gap — to help everyone understand how their genes influence their health, diet, and longevity with practical and useful information based on current research studies.
With my undergraduate degree in engineering as a foundation and a Master’s degree in Biological Sciences from Clemson University (2019), I’ve built Genetic Lifehacks into a platform that has helped over 4 million readers and 17,000 members to optimize their health through understanding their genetics.
~ Debbie