Detoxification & Medications (see all):

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  PFAS, Your Genes, and Your Health: From Mitochondrial Function to Immune Response
  PFAS are persistent “forever chemicals” found in everyday products that are used to make products water-resistant, stain-resistant, and non-stick. Research shows PFAS are associated with reproductive issues, immune suppression, thyroid dysfunction, and more.
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  Risk of Osteonecrosis from Bisphophonates
  A small percentage of people taking bisphosphonates will experience osteonecrosis – bone death – in the jaw. Genetic variants are part of the susceptibility.
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  ABCB1 (P-glycoprotein): Response to Medications, HRT, and Environmental Toxins
  ABCB1 encodes P-glycoprotein, a transporter that removes toxins – and medications – from the body. Genetic variants in the ABCB1 gene can affect how well a medication works for you.

Inflammation & Immune Response (see all):

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  Trigger Points, Myofascial Pain Syndrome, and Underlying Causes
  Trigger points are hyperirritated knots in the muscle and fascia that can refer pain to a nearby region of the body.
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  Specialized Pro-resolving Mediators (SPMs): The Resolution of Inflammation
  Chronic inflammation is at the root of all diseases. New research discusses how pro-resolving mediators are the key to the resolution of inflammation.
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  Epstein-Barr Virus: Genetic Risks, Reactivation, and Chronic Illnesses
  Epstein-Barr virus (EBV) impacts lifelong health, links to autoimmune diseases, genetic risk factors, and practical steps to reduce reactivation.

Brain Function and Mood Disorders (see all):

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  Neuropilins: Neurodevelopmental Disorders, Gut Barrier, & Covid Brain
  Neuropilins act as receptors and are found on the surface of cells. Learn about its many roles body, such as in the immune, vascular and nervous systems.
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  Trace Minerals and Neurocognitive Optimization
  Trace minerals affect neurotransmitter levels and neuroinflammation. Getting the right levels of micronutrients can help optimize neurocognitive function.
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  Hypnosis Genes: Genetic Influences on Hypnosis
  Not everyone is equally susceptible to hypnosis. Learn how your genetic variants play a role in how your brain focuses and responds to hypnotic suggestions.

Heart Health (see all):

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  APOB gene: Apolipoprotein B Levels and Health Risks
  ApoB is a better predictor of heart disease risk than LDL-C or total cholesterol. Genetic variants can increase or decrease ApoB levels.
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  Lactate, Lactate Dehydrogenase, and Lactate Transporters
  Lactate is much more than a workout byproduct—it’s a key energy source, signaling molecule, and regulator of metabolism, brain health, and disease.
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  Elevated Fibrinogen: Risk factor for blood clots
  Fibrinogen is a protein that is essential for creating blood clots when you get a wound. But higher levels of fibrinogen are a major risk factor for heart disease and DVT. Learn how your genes impact your fibrinogen level.

Supplements and Your Genes (see all):

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  BPC-157: Tendon Repair and More
  BPC-157  (body protection compound-157) is a peptide derived from human gastric juice that is 15 amino acids in length. Studies show that it promotes the healing of different tissues, including skin, muscle, bone, and tendons.
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  Thymosin Beta 4: Genetics & Supplemental Peptides
  Thymosin beta 4 is a natural peptide that is made in the body and helps with wound healing, muscle recovery, and decreasing inflammation. It is also available as a supplemental peptide.
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  Cordyceps: Clinical Trials, Mechanism of Action, and Genetic Connections
  Cordyceps mushroom extract has immunomodulatory and anti-inflammatory effects. Studies show benefits for asthma, resistance training, endurance training, and kidney disease.

Metabolic Health (see all):

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  Very Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD)
  VLCAD deficiency causes the mitochondria to be unable to use long-chain fatty acids for energy production. This can result in hypoglycemia or mitochondrial dysfunction.
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  FTO and m6A Methylation
  Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
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  Medium Chain Acyl-CoA Dehydrogenase Deficiency: Check your genetic data
  Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is an “inborn error of metabolism” which impairs the body’s ability to break down medium-chain fatty acids for fuel. Learn more about this metabolic disorder.

Longevity & Healthspan (see all):

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  Snoring: Genes and Solutions
  Genetics plays a role in snoring —certain genes affect airway structure, fat distribution, and muscle control.
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  Problems sleeping? Your genes can point to individualized solutions
  Overview how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes.
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  How to Shift Your iPhone Screen to Red at Night
  Learn how to shift your iphone screen to be completely red at night (no blue light) with a triple-click of the power button.

Nutrigenomics (see all):

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  Molybdenum: Genetic Connections, Sulfur Metabolism, and Cofactor Deficiency
  Molybdenum is a trace mineral needed in the right amounts for sulfur detoxification and the formation of uric acid.
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  Oxalates: What Your Genes and Diet Say About Oxalate Health Issues
  Green smoothies have been a health fad for quite a while now, but these health drinks can be a double-edged sword for some people due to their high oxalate content. Find out if you are genetically prone to kidney stones and what to do about it.
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  FOLR1 and FOLR2: Transporting Folate, Folinic Acid, and Folic Acid into Cells
  Genetic variants in the FOLR1 and FOLR2 genes (folate receptors alpha and beta) can impact folate in the brain and in the immune response.

Sleep & Circadian Rhythm (see all):

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  Snoring: Genes and Solutions
  Genetics plays a role in snoring —certain genes affect airway structure, fat distribution, and muscle control.
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  Problems sleeping? Your genes can point to individualized solutions
  Overview how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes.
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  How to Shift Your iPhone Screen to Red at Night
  Learn how to shift your iphone screen to be completely red at night (no blue light) with a triple-click of the power button.

Hormones (see all):

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  Testosterone: Genetic Variants that Impact Testosterone Levels
  While diet and lifestyle play a role in testosterone levels, in males, there is a strong genetic component as well. Check out your genes to see if they are playing a role in your low T levels — and then check out the Lifehacks.
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  HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions
  Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
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  Thyroid Hormones: Genes, Hypothyroidism, and T4/T3 Conversion
  The thyroid is a master regulator controlling many of your body’s systems. It is integral for metabolism and body temperature. Learn more about specific thyroid-related variants and check your genetic raw data.

Athletics & Exercise (see all):

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  Lactate, Lactate Dehydrogenase, and Lactate Transporters
  Lactate is much more than a workout byproduct—it’s a key energy source, signaling molecule, and regulator of metabolism, brain health, and disease.
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  Resistance Training Genetics: Personalized Muscle Building
  Learn how genetics and lifestyle factors influence muscle growth from resistance training. Covers the science behind strength gains, from molecular pathways to genetic applications backed by research.
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  Skinny Genes: Weight Loss from Aerobic Exercise
  Researchers have found that weight loss from aerobic exercise depends on your genetic variants. Find out if you have skinny genes from exercise.

Traits (see all):

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  Skinny Genes: Weight Loss from Aerobic Exercise
  Researchers have found that weight loss from aerobic exercise depends on your genetic variants. Find out if you have skinny genes from exercise.
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  Dyslexia: Genes + Early Life Stressors
  While dyslexia is known to run in families, the role of genetics in dyslexia is still being determined. Here is a quick look at some of the genes involved in dyslexia, affecting around 10% of the population.
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  Mosquito Bite Genes: Are you a mosquito magnet?
  Do you feel like you are a magnet for mosquitoes? Genetic variants do play a role in how attractive you are to mosquitoes.

Pregnancy & Infertility (see all):

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  Pregnancy: How Your Genes affect the Nutrients You Need
  Pregnancy is a time of increased nutritional needs, and your genes can help you dial in your diet to prevent nutrient deficiencies.
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  Trying to get pregnant? Targeted Approaches to Improving Egg Quality
  Trying to get pregnant? Healthy eggs are vital for a successful pregnancy. Discover four key ways to improve your egg quality, according to research studies.
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  Folate Optimization: MTHFR and Fertility
  MTHFR variants affect the conversion of folate into the active form. Learn how this can affect you if you are trying to get pregnant.

Disease Prevention (see all):

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  Risk of Osteonecrosis from Bisphophonates
  A small percentage of people taking bisphosphonates will experience osteonecrosis – bone death – in the jaw. Genetic variants are part of the susceptibility.
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  FTO and m6A Methylation
  Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
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  Building Up Iron: Hemochromatosis Mutations
  A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.

Autoimmune Diseases (see all):

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  Raynaud’s: Causes, Symptoms, and Genetics
  Do your fingertips turn white and blue when cold? Discover the causes and symptoms of Raynaud’s syndrome and your genetic susceptibility.
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  Celiac Genes: How to Check Your Raw Data
  Celiac disease is caused by a combination of environmental factors (eating gluten, other factors) and having the genetic variants that cause susceptibility to the disease. Without the genetic susceptibility, you won’t have celiac.
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  Thyroid Hormones: Genes, Hypothyroidism, and T4/T3 Conversion
  The thyroid is a master regulator controlling many of your body’s systems. It is integral for metabolism and body temperature. Learn more about specific thyroid-related variants and check your genetic raw data.

Mitochondrial Health (see all):

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  Very Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD)
  VLCAD deficiency causes the mitochondria to be unable to use long-chain fatty acids for energy production. This can result in hypoglycemia or mitochondrial dysfunction.
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  Carnitine: Genetic Variants Affecting Mitochondrial Energy and Health
  Learn how carnitine powers cellular energy, supports organ health, and influences metabolism. Discover its benefits for brain, liver and immune function, plus how genetics affect your carnitine needs.
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  Thiamine: Genomics, Cellular Energy, and Cognitive Function
  Also known as vitamin B1, thiamine is essential for energy production and brain function. Learn how your genes influence your need for thiamine.