
Optimize your health now by understanding your genes.
Genetic Lifehacks gives you the tools to use your genetic raw data. Discover personalized health and wellness solutions right for you.
Use your genetic raw data from 23andMe, AncestryDNA, MyHeritage, and more.
- Privacy: Your genetic raw data stays securely on your own computer – it isn’t uploaded or stored on Genetic Lifehacks. Everything happens browser-side.
- Learn: Understand how your genes influence nutrition, supplements, longevity, disease risk, wellness, and more.
- Apply: See your genotypes, research-backed solutions, and decide what works best for you.
Already a member? Sign in here.
Latest Articles and Genotype Reports:
Brain Function and Mood Disorders (see all):
- Hypnosis Genes: Genetic Influences on HypnosisNot everyone is equally susceptible to hypnosis. Learn how your genetic variants play a role in how your brain focuses and responds to hypnotic suggestions.
- Lactate, Lactate Dehydrogenase, and Lactate TransportersLactate is much more than a workout byproduct—it’s a key energy source, signaling molecule, and regulator of metabolism, brain health, and disease.
- Reelin – Long Covid, Depression, and Alzheimer’sReelin is a key glycoprotein involved in brain development, cognition, and neurodegenerative diseases like Alzheimer’s, schizophrenia, autism, and cardiovascular health.
- Oxalates:What Your Genes and Diet Say About Oxalate Health IssuesGreen smoothies have been a health fad for quite a while now, but these health drinks can be a double-edged sword for some people due to their high oxalate content. Find out if you are genetically prone to kidney stones and what to do about it.
- FOLR1 and FOLR2: Transporting Folate, Folinic Acid, and Folic Acid into CellsGenetic variants in the FOLR1 and FOLR2 genes (folate receptors alpha and beta) can impact folate in the brain and in the immune response.
- Carnitine: Genetic Variants Affecting Mitochondrial Energy and HealthLearn how carnitine powers cellular energy, supports organ health, and influences metabolism. Discover its benefits for brain, liver and immune function, plus how genetics affect your carnitine needs.
- Lactate, Lactate Dehydrogenase, and Lactate TransportersLactate is much more than a workout byproduct—it’s a key energy source, signaling molecule, and regulator of metabolism, brain health, and disease.
- Elevated Fibrinogen: Risk factor for blood clotsFibrinogen is a protein that is essential for creating blood clots when you get a wound. But higher levels of fibrinogen are a major risk factor for heart disease and DVT. Learn how your genes impact your fibrinogen level.
- BPIFB4 Gene: Linked to Longevity and Heart HealthDiscover the impact of the BPIFB4 gene on longevity and immunity, and find out if you have the longevity variant in your genotype report.
Supplements and Your Genes (see all):
- Cordyceps: Clinical Trials, Mechanism of Action, and Genetic ConnectionsCordyceps mushroom extract has immunomodulatory and anti-inflammatory effects. Studies show benefits for asthma, resistance training, endurance training, and kidney disease.
- Methylene Blue: Genetic Connections and Research StudiesMethylene blue has neuroprotective and anti-inflammatory properties, but it isn’t for everyone. Learn about the genetic variants that throw a caution flag on this one.
- Resveratrol: Studies, Genetic Interactions, and BioavailabilityResveratrol is a polyphenol with anti-inflammatory and antioxidant properties. Studies show that it affects heart health, bone health, cognitive function, and metabolic health.
Athletics & Exercise (see all):
- Lactate, Lactate Dehydrogenase, and Lactate TransportersLactate is much more than a workout byproduct—it’s a key energy source, signaling molecule, and regulator of metabolism, brain health, and disease.
- Resistance Training Genetics: Personalized Muscle BuildingLearn how genetics and lifestyle factors influence muscle growth from resistance training. Covers the science behind strength gains, from molecular pathways to genetic applications backed by research.
- Skinny Genes: Weight Loss from Aerobic ExerciseResearchers have found that weight loss from aerobic exercise depends on your genetic variants. Find out if you have skinny genes from exercise.
Inflammation & Immune Response (see all):
- Specialized Pro-resolving Mediators (SPMs): The Resolution of InflammationChronic inflammation is at the root of all diseases. New research discusses how pro-resolving mediators are the key to the resolution of inflammation.
- Epstein-Barr Virus: Genetic Risks, Reactivation, and Chronic IllnessesEpstein-Barr virus (EBV) impacts lifelong health, links to autoimmune diseases, genetic risk factors, and practical steps to reduce reactivation.
- Mast Cells: MCAS, Genetics, and SolutionsMast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.
- Testosterone: Genetic Variants that Impact Testosterone LevelsWhile diet and lifestyle play a role in testosterone levels, in males, there is a strong genetic component as well. Check out your genes to see if they are playing a role in your low T levels — and then check out the Lifehacks.
- HPA Axis Dysfunction: Understanding Cortisol and Genetic InteractionsCortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
- Thyroid Hormones: Genes, Hypothyroidism, and T4/T3 ConversionThe thyroid is a master regulator controlling many of your body’s systems. It is integral for metabolism and body temperature. Learn more about specific thyroid-related variants and check your genetic raw data.
Sleep & Circadian Rhythm (see all):
- Snoring: Genes and SolutionsGenetics plays a role in snoring —certain genes affect airway structure, fat distribution, and muscle control.
- Problems sleeping? Your genes can point to individualized solutionsOverview how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes.
- How to Shift Your iPhone Screen to Red at NightLearn how to shift your iphone screen to be completely red at night (no blue light) with a triple-click of the power button.
Longevity & Healthspan (see all):
- Snoring: Genes and SolutionsGenetics plays a role in snoring —certain genes affect airway structure, fat distribution, and muscle control.
- Problems sleeping? Your genes can point to individualized solutionsOverview how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes.
- How to Shift Your iPhone Screen to Red at NightLearn how to shift your iphone screen to be completely red at night (no blue light) with a triple-click of the power button.
- Skinny Genes: Weight Loss from Aerobic ExerciseResearchers have found that weight loss from aerobic exercise depends on your genetic variants. Find out if you have skinny genes from exercise.
- Dyslexia: Genes + Early Life StressorsWhile dyslexia is known to run in families, the role of genetics in dyslexia is still being determined. Here is a quick look at some of the genes involved in dyslexia, affecting around 10% of the population.
- Mosquito Bite Genes: Are you a mosquito magnet?Do you feel like you are a magnet for mosquitoes? Genetic variants do play a role in how attractive you are to mosquitoes.
- FTO and m6A MethylationRecently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
- Picking the Right Weight Loss Diet for Your GenesIs there an easy way to compare what diet might be best based on your genotype? Research shows some interesting associations between genotype and diet interactions and weight loss.
- Adenoviruses: Causing Weight Gain and ObesityThere have been several interesting studies linking obesity to a viral infection, specifically an adenovirus. Learn more about this virus and its association with obesity.
Pregnancy & Infertility (see all):
- Pregnancy: How Your Genes affect the Nutrients You NeedPregnancy is a time of increased nutritional needs, and your genes can help you dial in your diet to prevent nutrient deficiencies.
- Trying to get pregnant? Targeted Approaches to Improving Egg QualityTrying to get pregnant? Healthy eggs are vital for a successful pregnancy. Discover four key ways to improve your egg quality, according to research studies.
- Folate Optimization: MTHFR and FertilityMTHFR variants affect the conversion of folate into the active form. Learn how this can affect you if you are trying to get pregnant.
Detoxification & Medications (see all):
- Opioid Receptors Genetic Variants and AddictionGenetic variants in the ORPM1 gene impact both the amount of pain someone experiences and their response to opioid drugs. These variants are also important in susceptibility to opiate addiction. (Member’s article)
- Microplastics Research RoundupMicroplastics research shows that these microscopic bits of plastics are a real problem for health and wellness.
- BPA and BPS: How Your Genes Influence Bisphenol DetoxificationBPA, a chemical found in some plastics, has been linked to a variety of health issues in people. Learn more about BPA and the research into genetic responses to this chemical.
- FTO and m6A MethylationRecently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
- Building Up Iron: Hemochromatosis MutationsA couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.
- PCSK9: Cancer Recurrence & PreventionLower PCSK9 levels have been shown in research studies to correlate to a significantly reduced risk of metastatic recurrence in certain types of cancer.
Autoimmune Diseases (see all):
- Celiac Genes: How to Check Your Raw DataCeliac disease is caused by a combination of environmental factors (eating gluten, other factors) and having the genetic variants that cause susceptibility to the disease. Without the genetic susceptibility, you won’t have celiac.
- Thyroid Hormones: Genes, Hypothyroidism, and T4/T3 ConversionThe thyroid is a master regulator controlling many of your body’s systems. It is integral for metabolism and body temperature. Learn more about specific thyroid-related variants and check your genetic raw data.
- HLA-B27: Genetic Variant That Increases Susceptibility to Autoimmune DiseasesThe HLA-B27 serotype is linked to an increased risk of several autoimmune diseases, including ankylosing spondylitis, psoriatic arthritis, and IBD.
Mitochondrial Health (see all):
- Carnitine: Genetic Variants Affecting Mitochondrial Energy and HealthLearn how carnitine powers cellular energy, supports organ health, and influences metabolism. Discover its benefits for brain, liver and immune function, plus how genetics affect your carnitine needs.
- Thiamine: Genomics, Cellular Energy, and Cognitive FunctionAlso known as vitamin B1, thiamine is essential for energy production and brain function. Learn how your genes influence your need for thiamine.
- Glutathione: Master Antioxidant, Reducing Oxidative Stress, and DetoxificationGlutathione is an antioxidant produced in all cells to balance out ROS. Genetic variants can impact your glutathione levels, which can alter your ability to detoxify certain substances or withstand stressors in the body.
Explore by Symptoms, Supplements, Diet, or Pathway:
Symptoms
Supplements
Pathways & Processes
Diseases, Conditions
Lifestyle & Diet
Genes, Proteins
Hormones
Medications
Toxins
My Story…
Hi! I’m Debbie Moon. Welcome to Genetic Lifehacks.
When I first had my genetic data sequenced, I was both amazed at the research available in academic journals and frustrated by the difficult language and disconnected topics.
Genetic Lifehacks began as a way to share what I was learning about genetics with my family and friends.
My goal has always been to freely share information so that everyone can benefit.
As the website grew in popularity, I decided that I needed to know more… both more about genetics and more about how the pieces of the biological systems fit together. Since my undergraduate degree was in engineering, I went back to school and received my Master’s degree in Biological Sciences from Clemson University in 2019.
Now a full-time endeavor, Genetic Lifehacks has reached over 2.5 million readers, equipping people to use their genetic data to optimize their health.
~ Debbie Moon, Founder of Genetic Lifehacks